Pariet 20 mg 14 Tablets_1

Rabeprazole sodium. Class Antacids, Antireflux Agents & Antiulcerants Classification rabeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD) and Healing of Duodenal Ulcers. Dosage/Direction for Use The usual adult dose for oral use is20mg of sodium rabeprazole administered once daily .tablets should be taken in the morning, before eating . tablets should not be chewed or crushed, but should be swallowed whole. Renal and hepatic impairment: No dosage adjustment is necessary for patients with renal or hepatic impairment. Children: it is not recommended for use in children, as there is no experience of its use in this group. Contraindications Patients with known hypersensitivity to rabeprazole sodium, or to any excipient used in the formulation. It is contra-indicated in pregnancy and during breast feeding. Special Precautions Careful Administration in the following patients: Patients with a history of drug hypersensitivity; Patients with hepatic function disorder , patients with liver cirrhosis Elderly patients . Adverse Reactions Adverse reactions were reported in 22 of 1,244 patients (1.77%), and abnormal laboratory test values were reported in 82 (6.59%). (At the time of approval.) Clinically significant adverse reactions Shock Agranulocytosis, thrombocytopenia and pancytopenia Hepatic function disorders Interstitial pneumonia Interstitial Nephritis. Clostridium difficile associated diarrhea. Vitamin B12 Deficiency. Storage should be stored at room temperature not exceeding 30° C and protected from moisture after unsealing.